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Antoine is a town in Pike County, Arkansas state, along the Antoine River. The population was 156 at the 2000 census. The town is at a height of 300 feet above sea level.
During the Depression and afterwards, Antoine experienced a gradual but steady decline in population.
Today, the main activities include logging, ranching, truck farming, and tourism. Most residents work away from the town, in the nearby cities of Arkadelphia, Hope, or Nashville.