Dr. Isaac George, MD joined NewYork Presbyterian/Columbia University Medical Center in the Department of Surgery in July of 2001 as a resident in general surgery following his graduation from Duke University School of Medicine. Prior to receiving his MD, Dr. George completed a B.S. in Mechanical Engineering at Massachusetts Institute of Technology in 1997. Dr. George also completed a fellowship program in cardiothoracic surgery in 2011 as well as a fellowship program in interventional cardiology in 2012. Dr. George is an Associate Professor of Surgery and Medicine, and the Surgical Director of Structural Heart of the NYP health system.
Dr. George is board certified in thoracic (cardiac) surgery. He performs all types of open and reoperative adult cardiac surgery (aortic, mitral and tricuspid valve surgery, aortic aneurysm surgery, coronary bypass grafting, robotic surgery) with a particular interest in complex valvular disease. He specializes in minimally invasive mitral valve surgery with small incisions and repair of the mitral valve. He annually performs 150-200+ open heart surgeries a year and is the busiest heart surgeon by procedure volume in New York State. Dr. George is currently the Co-Director of the Structural Heart and Valve Center at Columbia University Medical Center. His surgical outcomes remain some of the best in the state despite taking on the highest risk cases (surgical mortality rate per year ~1.5%).
Dr. George is focused on integrating new technology and innovation into his clinical practice. He is one of the few physicians in the world trained in both cardiac surgery and interventional cardiology. He is an expert in the most current and cutting-edge procedures including Transcatheter Aortic Valve Replacement (TAVR), transcatheter valvular mitral valve repair (Mitraclip, Edge to Edge), transcatheter mitral and tricuspid valve replacement and surgical TAVR removal/explantation. He performs almost 800 transcatheter valve procedures a year, in addition to his busy open surgical practice and has personally done almost 8000 TAVR procedures. Because he is trained in multiple disciplines, he is able to combine strategies to create a treatment plan for each individual patient that is both unbiased and personalized. As Primary Investigator of numerous national surgical and transcatheter trials, he has extensive clinical research trial experience.
There are numerous new transcatheter trials for aortic stenosis, aortic insufficiency, bicuspid aortic valves, mitral regurgitation, tricuspid regurgitation, and heart failure that Dr. George is involved. Click here for a full list and description of ongoing trials.
Dr. George is involved in both benchtop and clinical research as well. His projects reflect the translational nature of the lab as well as his clinical interests. His clinical practice allows him to be uniquely positioned to advance this research with a clinical endpoint and potential therapeutic intervention as the goal.
Dr. George can be contacted directly at ig2006@cumc.columbia.edu
Watch: Meet Cardiothoracic Surgeon, Dr. Isaac George
Watch: Dr. Isaac George Discusses Advancements in Heart Valve Surgery
Watch: Dr. George talks Minimally Invasive Mitral Valve Surgery
Watch: Decision Making in Aortic Valve Disease with Dr. Isaac George
Watch: Dr. George Discusses Stroke Risk and TAVR
Watch: Dr. George Interviewed on the Doctors Podcast
Read: Dr. George Talks Hybrid Cardiac Surgery: A Viable Strategy for Select Patients
Read: What To Expect After A Coronary Artery Bypass, According To Dr. George
Read: Dr. George Participates in World's First Use of Medical Device to Protect From Stroke During TAVR
Read: Dr. George On Expanded Transcatheter Options for Cardiac Patients
Read: Dr. George on Innovations in Hybrid Surgery
Dr. George hosts Taking it to Heart, the Columbia Heart Valve team's podcast. In each episode, Dr. George and the Columbia Heart Valve team discuss a new topic related to valvuar disease. Subscribe to Taking It to Heart.
Click here for a full list and description of ongoing trials from Dr. George.
Click here for a complete list of publications from Dr. George.
Click here to read patient reviews of Dr. George.
Watch: Recovery from COVID
Disclosures:doctor-isaac-george-trials-
consultant (honoraria) – Zimmer Biomet, Atricure, Neosurgery, Neptune Medical, Abbvie,  Johnson & Johnson, Durvena, Boston Scientific, Edwards Lifesciences, Medtronic, Help-TheraX, 3ive, Encompass, Summus Medical, Abbott SJM, BCI, Xeltis
Advisory Boards: Edwards Surgical, Medtronic Surgical, Medtronic Structural Mitral & Tricuspid, Trisol Medical, Valcare Medical, Durvena, Abbvie, Johnson & Johnson, Foldax Medical, Zimmer Biomet, Neosurgery, Abbvie, Boston Scientific, Summus Medical, BCI
Equity: Valcare Medical, Durvena, CardioMech, Vdyne, MitreMedical, MITRx, BCI
Institutional funding to Columbia University: Edwards Lifesciences, Medtronic, Abbott Vascular, Boston Scientific, JenaValve.