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Osceola is a city located in the U.S. state of Arkansas. It is within and one of the county seats of Mississippi County. It was incorporated in 1853. It has a total area of 9.79 square miles at 35°42′8″N 89°58′33″W. The elevation is 246 feet above sea level. As of the 2010 census data, it had a total population of 7,757. The population density was 723.80/sq mi. Estimated per capita income in 2015 was $16,640. It has Zip code 72370.